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Immune cell infiltration was evaluated via single-sample gene set enrichment (ssGSEA) analysis and systematically correlated with genomic characteristics and clinicopathological features of IDC patients. Method: In this study, we depict the immune landscape of IDC by using transcriptome profiling and clinical characteristics retrieved from The Cancer Genome Atlas (TCGA) data portal. Tumor microenvironment (TME) immune phenotypes play crucial roles in predicting clinical outcomes and therapeutic efficacy. 6Department of Pharmacy, Pharmaceutical Biotechnology, Center of Nanoscience (CeNS), Ludwig Maximilian University of Munich, Munich, Germanyīackground: Invasive ductal carcinoma (IDC) is a clinically and molecularly distinct disease.5College of Life Sciences, Nanjing University, Nanjing, China.4Department of Cardiology, School of Medicine, Sir Run Run Shaw Hospital, Zhejiang University, Hangzhou, China.3Department of Radiation Oncology, University Hospital, Ludwig Maximilian University of Munich, Munich, Germany.2Technical University Munich, Munich, Germany.1Helmholtz Center Munich, German Research Center for Environmental Health, Institute of Radiation Biology, Munich, Germany.

Xuanwen Bao 1,2 * †, Run Shi 3 †, Kai Zhang 4, Shan Xin 1, Xin Li 5, Yanbo Zhao 4 and Yanfang Wang 6 *